Quiz: The Alcohol-Cancer Connection

Laura A. Stokowski, RN, MS

Disclosures

November 23, 2015

The flushing response is predominantly because of an inherited deficiency in the enzyme aldehyde dehydrogenase 2 (ALDH2) and is relatively common, occurring in about 36% of East Asians.[14] Alcohol consumed by ALDH2-deficient individuals is metabolized to acetaldehyde, which accumulates in the body owing to absent ALDH2 activity and results in facial flushing, nausea, and tachycardia.[15] Long-time or heavy drinkers can develop tolerance to severe acetaldehydemia; consequently, someone with a history of facial flushing after alcohol ingestion but who no longer exhibits this reaction might still be deficient in ALDH2 activity.[16]

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.

processing....