Roflumilast Partially Reverses Smoke-induced Mucociliary Dysfunction

Andreas Schmid; Nathalie Baumlin; Pedro Ivonnet; John S. Dennis; Michael Campos; Stefanie Krick; Matthias Salathe

Disclosures

Respiratory Research. 2015;16(135) 

In This Article

Conclusion

Our results show that roflumilast increases ASL volume and CBF in fully differentiated NHBE cells exposed to smoke by increasing [cAMP]i and in part, by enhancing apical chloride efflux via CFTR.

Comments

3090D553-9492-4563-8681-AD288FA52ACE

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