Aching Joints in Diabetes: What Drug Is at Fault?

Douglas S. Paauw, MD


November 05, 2015

Those Aching Joints

A 48-year-old woman presents with marked pain in her wrists and ankles. The pain has been present for 2 weeks, and she describes it as "increasingly disabling."

Her medical history is significant for hypertension, type 2 diabetes mellitus (T2DM), gastroesophageal reflux disease, and obesity. Her current medications are amlodipine, hydrochlorothiazide, sitagliptin, metformin, omeprazole, and lorcaserin. On physical examination, you find no swelling or erythema of her joints.

Her most recent laboratory values are:

  • Blood urea nitrogen: 10 mg/dL; and

  • Creatinine: 0.8 mg/dL.


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