16th World Conference on Lung Cancer (WCLC) Presidential Symposium: Summary and Clinical Implications

Gilberto Lopes, MD, MBA


October 12, 2015

In This Article

Stopping Smoking After CT Lung Cancer Screening

The fourth and final presentation at the main plenary session showed that smoking cessation in the setting of lung cancer screening with low-dose CT decreases mortality. Between 2000 and 2010, Italian investigators enrolled 3381 heavy smokers, 50 years or older, in low-dose CT screening programs. Most patients were men, and median smoking exposure was 40 pack-years.

With a total of 32,858 person-years in the study,[7] the HR for mortality was significant lower for patients who stopped smoking after participating in screening with low-dose CT as compared with those who continued to smoke (HR=0.57; 95% CI, 0.38-0.85). The number of deaths/100 person-years was 565 in the group that quit smoking and 846 for those who did not. As such, patients who smoke and participate in screening programs have lower death rates when they quit.


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