Supraciliary Stents as an Alternative to Filtering Surgery in Open-Angle Glaucoma

Shuchi B. Patel, MD


July 21, 2015

Supraciliary Micro-stent Implantation for Open-Angle Glaucoma Failing Topical Therapy: 1-Year Results of a Multicenter Study

Garcia-Feijoo J, Rau M, Grisanti S, et al
Am J Ophthalmol. 2015;159:1075-1081

Study Summary

This study by Garcia-Feijoo and colleagues is the first report of the Study of CyPass Implantation In Patients With Open Angle Glaucoma Refractory to Single or Multi-agent Topical Therapy (DUETTE clinical study).

In this study, as opposed to some other previously published data, the implantation of a supraciliary micro-stent (CyPass® Micro-Stent; Transcend Medical, Menlo Park, California) was a stand-alone procedure and not combined with phacoemulsification.

This single-armed, multicenter, prospective study evaluated the effect of the supraciliary stent in patients who were eligible for conventional filtering surgery for uncontrolled glaucoma. The 1-year data from the 65 patients who were enrolled demonstrated that the micro-stent lowers intraocular pressure (IOP) and is an effective surgical treatment for glaucoma. Mean IOP was reduced by more than 30%, and the mean number of medications used also decreased from 2.2 to 1.4. Further filtering surgery was not needed in over 80% of patients.

No major adverse events occurred. Intra- and postoperative complication rates were low and limited to treatable events such as cataract progression and transient IOP elevation, as opposed to more vision-threatening complications seen with standard filtering procedures.


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