Biologic Treatments for OA: A Sports Medicine Perspective

Sideline Consult

Bert R. Mandelbaum, MD, DHL (Hon)


July 15, 2015

Prolonging Activity in Aging Patients

But it's not too early to make some use of biologic treatments. In my own practice, we stabilize the ligaments; resurface the cartilage defect with cells, scaffolds, and growth factors; regenerate the bone with stem cells; repair the menisci or replace them with cadaver allograft when appropriate; and correct any misalignment. We then protect the joint and facilitate healing with hyaluronic acid viscosupplementation and platelet-rich plasma. It is always about being comprehensive and utilizing a spectrum of care options.

We to talk to the patient about lifestyle factors such as obesity that can influence osteoarthritis. And we ask questions about hormonal balance and measure serum estrogen levels, counseling patients about the risk for osteoarthritis related to hormone deficiency.

The future holds nothing but promise in the treatment of this disabling disease. And the successful treatment of knee injuries has huge implications for our aging population. Maintaining a high level of activity is essential to good health in aging.[21]

More and more people can, and should, continue running, bicycling, dancing, and even playing basketball and soccer late in life. It's incumbent on us as sports physicians to make this possible.


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