Previous reports have shown that a low concentration of serum 25-OH vitamin D increases the risk of developing diabetes later in life and is also associated with an increased risk of diabetic microvascular complications, though our study only showed such associations for nephropathy. The vitamin D status of patients with diabetes should be considered during their regular follow-up, and supplementation should be provided to those at risk of deficiency.
Limitations of the Study
Because this was as a retrospective study, all patient data could not be fully retrieved. There is a need for prospective or controlled studies with larger sample sizes where vitamin D replacement and complication regressions are followed and where the impact of the vitamin D levels on blood glucose regulation is observed.
BMC Endocr Disord. 2015;15(33) © 2015 BioMed Central, Ltd.