Mitochondrial Causes of Epilepsy: Evaluation, Diagnosis, and Treatment

Hannah E. Steele, MBBS, MRCP; Patrick F. Chinnery, PhD, FRCP, FRCPath


Semin Neurol. 2015;35(3):300-309. 

In This Article

Mitochondrial Syndromes Associated With Infrequent Seizures

In contrast to the conditions described above, seizures are an uncommon phenotypic feature of many other classical mitochondrial disorders, including

  • Neuropathy, ataxia, retinitis pigmentosa (NARP)[46]

  • Kearns–Sayre syndrome (KSS)[47,48]

  • Leber's hereditary optic neuropathy (LHON)[49,50]

  • Maternally inherited diabetes and deafness (MIDD)[1]