Statins and Antibiotics: Which Combination Is Safest?

Douglas S. Paauw, MD


June 02, 2015

What Is the Safest Antibiotic for This Patient With Comorbidities?

A 65-year-old man presents with cough and fever. He has had severe diarrhea for 2 days. He reports that he was on a cruise with a friend who was diagnosed with Legionella infection yesterday.

The patient's medical history is significant for type 2 diabetes, hyperlipidemia, and hypertension. His current medications include lisinopril, simvastatin, amlodipine, gemfibrozil, and metformin.

You obtain a chest radiograph, which shows patchy bilateral infiltrates. A routine panel of laboratory tests is significant for a white blood cell count of 17,000 cells/mL and a sodium level of 125 mEq/L.


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