Recommendations for Further Research
Larger, longer randomized, double-blind trials are needed to strengthen the recommendation of the use of probiotics as prophylaxis for recurrent UTIs in women. Future studies should examine optimum frequency, duration, species, and route of Lactobacilli. In addition, future trials should examine the role of probiotic-rich diets in altering vaginal microbiome to prevent recurrent UTIs. In an age of increasing antimicrobial resistance, other non-antibiotic methods of preventing recurrent UTIs, such as cranberry tablets, herbs, and acupuncture, should also be further studied, especially in comparative effectiveness re - search with Lactobacilli. Data on the long-term effects of prolonged antibiotic use would also be helpful in evaluating the pros and cons of antibiotics and probiotics.
Urol Nurs. 2015;35(1):18-21. © 2015 Society of Urologic Nurses and Associates