A Review of Vitamin B12 in Dermatology

Jennifer Brescoll; Steven Daveluy


Am J Clin Dermatol. 2015;16(1):27-33. 

In This Article


Cobalamin is an important vitamin for the proper function of the human body, and deficiency is fairly prevalent with advanced age. The dermatologist can play a role in the diagnosis of deficiency by recognizing its mucocutaneous manifestations. It is also important to recognize cutaneous complications of cobalamin therapy, since many patients are undergoing therapy. Associations exist between cobalamin and dermatologic diseases such as vitiligo, atopic dermatitis, and aphthous stomatitis. Further elucidation of the exact interplay between these diseases and cobalamin may lead to advances in diagnosis and treatment.