Stereotactic Laser Ablation of High-Grade Gliomas

Ammar H. Hawasli, M.D., Ph.D.; Albert H. Kim, M.D., Ph.D.; Gavin P. Dunn, M.D., Ph.D.; David D. Tran, M.D., Ph.D.; Eric C. Leuthardt, M.D.


Neurosurg Focus. 2014;37(6):e1 

In This Article


A comprehensive search of the English literature was performed using PubMed ( and Google Scholar ( Clinical research articles on stereotactic laser ablation for brain tumors were selected and evaluated for possible inclusion in the review. Inclusion criteria for study selection were as follows: 1) human study; 2) use of stereotactic laser ablation for brain tumors; and 3) at least a portion of the cohort reported had HGGs (WHO Grade III or IV gliomas). The study results also had to provide a Level IV or better level of evidence. This included randomized, controlled trials; prospective cohort studies; case-controlled studies; retrospective cohort studies; case series; and case reports. Expert opinions, reviews without presentation of clinical data, and reports without HGGs were excluded. Each article was thoroughly reviewed for details on treatments and outcomes.