Update on Endocrine Society Guidelines for Androgen Therapy in Women

Martha K. Richardson, MD


January 09, 2015

In This Article


Wierman ME, Arlt W, Basson R, et al. Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2014;99(10): 3489-3510.

The Endocrine Society Task Force continues to recommend against making a diagnosis of androgen deficiency syndrome in healthy women because a well-defined syndrome and data are lacking. The Task Force recommends against the general use of testosterone for the indications of infertility, sexual dysfunction (other than hypoactive sexual desire disorder), cognitive health, cardiovascular health, bone health, or general well-being. Because of limited data on effectiveness and safety, they recommend against routine use of dehydroepiandrosterone. They find that evidence supports short-term efficacy and safety of high physiologic doses of testosterone treatment of postmenopausal women with sexual dysfunction because of hypoactive sexual desire disorder. Any woman receiving testosterone therapy should be monitored for signs of androgen excess.