Cystic Renal Cell Carcinoma

A Report of 67 Cases Including 4 Cases With Concurrent Renal Cell Carcinoma

Shanwen Chen; Baiye Jin; Liqi Xu; Guanghou Fu; Hongzhou Meng; Ben Liu; Jun Li; Dan Xia


BMC Urol. 2014;14(87) 

In This Article


We reviewed our center's pathology files and identified all RCC cases with a cystic component occurring between January 2005 and April 2013; 67 cases of CRCC were identified. Clinical data, including clinical and radiographic characteristics, surgical management, pathologic features, and outcomes, were retrospectively reviewed.

Prior to surgery, patients underwent renal ultrasonography, abdominal computed tomography (CT), and magnetic resonance imaging (MRI) for evaluation of each patient's overall and renal status. All cystic masses were graded according to the Bosniak classification system,[1] and the pathological specimens were staged according to the tumor-node-metastasis (TNM) classification for RCC.[2] Additionally, a tumor nuclear grade was assigned using the Fuhrman system.[3] All histopathologic slides were reanalyzed by a single pathologist specialized in genitourinary pathology. The size of the neoplasm was measured grossly using the maximum diameter. Clinical follow-up data was obtained from patients' records as well as referring physicians; telephone interviews were conducted for patients who lacked clinical follow-up within the past 6 months. Finally, all data were analyzed using either the Student's t-test or a chi-square test.

The Medical Ethics Committee of the First Affiliated Hospital of Medical College, Zhejiang University approved this retrospective study; the study was exempted from the requirement to obtain informed consent from the other 63 patients (not including 4 cases of concurrent RCCs) in consideration of the nature of the study. Written informed consent was obtained from the 4 patients (4 cases of concurrent RCCs) for publication of this manuscript and accompanying images.