Pediatric Severe Sepsis: Current Trends and Outcomes From the Pediatric Health Information Systems Database

Amanda Ruth, MD; Courtney E. McCracken, PhD; James D. Fortenberry, MD, MCCM; Matthew Hall, PhD; Harold K. Simon, MD, MBA; Kiran B. Hebbar, MD, FCCM


Pediatr Crit Care Med. 2014;15(9):828-838. 

In This Article


PSS prevalence in PICUs has increased over the past decade, with an increased prevalence of comorbidities but a decrease in mortality. Individual center PSS prevalence, volume, and costs demonstrate variability and are significantly correlated with mortality. Further evaluation to identify clinical contributors to center-specific variability could identify opportunities for earlier sepsis identification and optimization of therapies.