A Natural Remedy for Canker Sores?

Eric T. Stoopler, DMD


October 16, 2014

Study Findings

The major results of the study were:

Topical honey was associated with more dramatic reduction in ulcer size compared with triamcinolone, which was associated with larger reductions than Orabase.

Pain in group 1 was reduced and eliminated faster than in groups 2 and 3, indicating higher effectiveness of honey than triamcinolone or Orabase for pain relief.

The time to resolution of erythema was fastest for group 1, followed by group 2 and then group 3.


Topical corticosteroids are widely used to treat a variety of oral mucosal diseases in addition to RAU, such as oral lichen planus, pemphigus vulgaris, and mucous membrane pemphigoid.[4] Most patients receive benefit from these agents when used appropriately, but common complaints about these medications include difficulty applying to the affected area, inability to adhere to the oral mucosa, dysgeusia, dysphagia, and cost.

Systemic absorption of these agents may be a significant issue for patients with such endocrine disorders as diabetes, and may negatively affect control of systemic disease.[5,6] Furthermore, some individuals may develop typical side effects of steroid use with these topical agents, whereas others may experience hypersensitivity reactions, which can range from mild to life-threatening.[6] For these reasons, alternatives to topical corticosteroids are frequently sought to treat human disease. This study suggests that honey may be a useful, natural remedy for RAU, a common oral condition encountered frequently in clinical practice.



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