Pregnancy-Specific Skin Disorders

Skyler White, BS; Rebecca Philips, MD; Megan Moody Neill, MD; Erica Kelly, MD


Skin Therapy Letter. 2014;19(5) 

In This Article


The four skin disorders specific to pregnancy, pemphigoid gestationis, polymorphic eruption of pregnancy, atopic eruption of pregnancy, and intrahepatic cholestasis of pregnancy, can be distinguished by clinical presentation, histopatholgy, pathogenesis, and potential for fetal complication. Only pemphigoid gestationis and intrahepatic cholestasis of pregnancy are associated with significant risk to the fetus. As these dermatoses are all characterized by pruritus, careful evaluation of any pregnancy related pruritus is essential to appropriately treat the mother and manage any potential risk to the fetus.