Treatment of Wounds Following Breast Reduction and Mastopexy With Subsequent Wound Dehiscence With Charged Polystyrene Microspheres

Oren Weissman, MD; Eyal Winkler, MD; Luc Teot, MD, PhD; Eric Remer, MD; Nimrod Farber, MD; Jonathan Bank, MD; Gabriel Hundeshagen, BMedSc; Isaac Zilinsky, MD; Josef Haik, MD, MPH


Wounds. 2014;26(2):37-42. 

In This Article


These preliminary findings suggest CPM might play a significant role in the future management of postoperative open wounds, and, more specifically, in open wounds after wound dehiscence following breast reductions. However, from the very nature of this case series, there is no control of confounders and bias. Because there is no control for bias, there is also the possibility that the treatment effect observed might be overestimated.[25,26]

The lack of homogeneity of the patients' wounds in this study appears to add to the strength of the observations, because while prognostic healing factors differed between patients, a comparable effect was demonstrated. The possible benefit of presenting this case series is that it helps form the basis of the evidence hierarchy required for any therapeutic intervention, and induces upcoming randomized controlled trials to further evaluate the impact of CPM on wounds. It should be noted that several other case studies are being conducted in the author's department, examining the use of CPM in other types of wounds, and are yielding promising results.