Treatment of Wounds Following Breast Reduction and Mastopexy With Subsequent Wound Dehiscence With Charged Polystyrene Microspheres

Oren Weissman, MD; Eyal Winkler, MD; Luc Teot, MD, PhD; Eric Remer, MD; Nimrod Farber, MD; Jonathan Bank, MD; Gabriel Hundeshagen, BMedSc; Isaac Zilinsky, MD; Josef Haik, MD, MPH


Wounds. 2014;26(2):37-42. 

In This Article

Material and Methods

Inclusion criteria consisted of patients that presented to the Department of Plastic and Reconstructive Surgery at the Sheba Medical Center, Tel-Aviv, Israel, with wound dehiscence following breast reduction or mastopexy (with or without implants) and subsequent open wounds. The wounds were surgically debrided, if necessary, until a clean wound bed was achieved (ie, no necrotic tissue was present) and then treatment with CPM was commenced. In accordance with the manufacturer's instructions, the CPM suspension was applied directly over the clean open wounds once daily, and then covered with sterile gauze that was soaked with the rest of the suspension. Dressings were left in place for 12 hours, after which the remaining suspension in the bottle (15 CC) was applied over the same gauze without changing it. No systemic or local antibiotic regimens were administered. Wounds were evaluated and documented via digital photography daily. Wound closure rates were measured manually (in millimeters) and any adverse reactions (ie, local infection or allergic response) were documented. Following wound closure, the patients were discharged and follow-up continued periodically in the outpatient clinic.