The Silver Tsunami Quiz: CVD in the Elderly

Adam H. Skolnick, MD


August 21, 2014

Diagnosing HFpEF is challenging in older adults.[9] The BNP level normally rises with increased chronological age, although levels 2-3 times the upper limit of normal are still useful in the diagnosis.[10]

The majority of elderly patients with HFpEF are women with hypertension.[11] Echocardiographic features, in particular the mitral Doppler inflow pattern, are less specific in older adults because there is normal physiologic dependence on late, active filling with increasing age.[12]

Elderly patients with HFpEF have more comorbidities and less physiologic reserve than younger patients; however, exertional dyspnea is not a normal part of aging, and an underlying cause should be sought.

Clinical Trials

Older adults are often underrepresented in clinical trials of cardiovascular disease. Various endeavors are under way to increase the number of older adults in clinical trials to a proportion representative of the proportion with a given disease.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as: