Primary Spine Tumors: Diagnosis and Treatment

Michelle J. Clarke, MD; Ehud Mendel, MD; Frank D. Vrionis, MD, PhD


Cancer Control. 2014;21(2):114-123. 

In This Article

Recurrence/Late Metastasis

If a patient has local recurrence or distant metastasis, then further treatment and possible restaging are both warranted. In the case of distant metastasis, the mainstay of treatment is adjuvant radiation and chemotherapy, although accessible solitary lesions may be amenable to resection. Local recurrence presents a different challenge. Provided no distant lesions are present during the metastatic workup, pursuing treatment as though it was a disrupted primary lesion might be appropriate. Although such a patient is likely to have a higher risk of repeat local recurrence than a patient undergoing first-time en bloc resection, initiating treatment may prevent late distant metastasis. However, it is worth noting that, in certain tumor types, survival may be related to local recurrence more than distant metastases. Due to the rarity of these lesions, little data exist on the efficacy of en bloc resection for recurrence.