A Randomized Prospective Multicenter Trial of Pancreaticoduodenectomy With and Without Routine Intraperitoneal Drainage

*Fisher exact test.
†T test; others: χ2 test.
ASA indicates American Society of Anesthesiologists; 1, a normal healthy patient; 2, a patient with mild systemic disease; 3, a patient with severe systemic disease; 4, a patient with severe systemic disease that is a constant threat to life.

*T test.
†Wilcoxon rank sum test; others: χ ² test.
CT indicates computed tomography; MRI, magnetic resonance imaging; POD, postoperative day; RBC, red blood cell; US, ultrasound.

*Fisher exact test.
†Wilcoxon rank sum test; others: χ² test.

Fisher exact test for all.

Authors and Disclosures

George Van Buren II, MD*, Mark Bloomston, MD†, Steven J. Hughes, MD‡, Jordan Winter, MD§, Stephen W. Behrman, MD¶, Nicholas J. Zyromski, MD||, Charles Vollmer, MD**, Vic Velanovich, MD††, Taylor Riall, MD‡‡, Peter Muscarella, MD†, Jose Trevino, MD‡, Attila Nakeeb, MD||, C. Max Schmidt, MD||, Kevin Behrns, MD‡, E. Christopher Ellison, MD†, Omar Barakat, MD*, Kyle A. Perry, MD†, Jeffrey Drebin, MD†, Michael House, MD†, Sherif Abdel-Misih, MD†, Eric J. Silberfein, MD*, Steven Goldin, MD††, Kimberly Brown, MD‡‡, Somala Mohammed, MD*, Sally E. Hodges, BS*, Amy McElhany, MPH*, Mehdi Issazadeh, BS*, Eunji Jo, MS*, Qianxing Mo, PhD* and William E. Fisher, MD

*Baylor College of Medicine, The Elkins Pancreas Center, Michael E. DeBakey Department of Surgery, and The Dan L. Duncan Cancer Center, Houston, TX; †Department of Surgery, The Ohio State University, Columbus, OH; ‡Department of Surgery, University of Florida, Gainesville, FL; §Department of Surgery, Jefferson Medical College, Philadelphia, PA; ¶Department of Surgery, Baptist Memorial Hospital/The University of Tennessee Health Science Center, Memphis, TN; ||Department of Surgery, Indiana University, Indianapolis, IN; **Department of Surgery, University of Pennsylvania, Philadelphia, PA; ††Department of Surgery, University of South Florida, Tampa, FL; and ‡‡Department of Surgery, The University of Texas Medical Branch, Galveston, TX.

Disclosure
This trial was funded by the Rodrick A. MacDonald Foundation (11RD1004) and partially funded by the Cancer Prevention and Research Institute of Texas (CPRIT) grant (RP101353) and the Dan L. Duncan Cancer Center Support grant (CA125123). The authors declare no conflicts of interest.

Reprints
William E. Fisher,MD, The Elkins Pancreas Center,Michael E. DeBakey Department of Surgery, Baylor College of Medicine, 6620 Main St, Ste 1450, Houston, TX 77030. E-mail: wfisher@bcm.edu.