Characteristics and Factors Associated With the Clinical Forms of Lipoatrophy During Highly Active Antiretroviral Therapy in Ouagadougou, Burkina Faso

Oumar Guira, MD; Hervé Tiéno, MD; Bertille Yaméogo, MD; Arnaud Eric Diendéré, MD; Nina Korsaga, MD; Yempabou Sagna, MD; Lassané Zoungrana, MD; Ismael Diallo, MD; René Traoré, MD; Joseph Youssouf Drabo, MD


J Int Assoc Provid AIDS Care. 2014;13(2):184-187. 

In This Article

Materials and Methods

This was a cross-sectional study conducted from March 10 to November 10, 2011, in Yalgado Ouédraogo Teaching Hospital (CHUYO), Ouagadougou, Burkina Faso. The study included HIV-infected adults (18 years or older) receiving ARV medications for at least 6 months and who were followed in the day care hospital of the internal medicine department and had consented to participate in the study. Those with edema and/or a Karnofsky performance status <70% were not included. The sample was accidental and nonprobabilistic. Isolated lipoatrophy was defined as a loss of subcutaneous fat in the face, buttocks, and upper and/or lower limbs. Mixed syndrome was defined as the coexistence of lipoatrophy and lipohypertrophy with fat accumulation in the abdominal, neck, breast, and/or pubic regions. The diagnosis was clinical and determined by the same investigator in accordance with the patient's opinion. Demographic, anthropometric, clinical, biological, and therapeutic variables were collected during the medical consultation and from the patients' clinical records. Analysis was performed using chi-square or Fisher (when size <5) test to compare qualitative variables. A P value of less than .05 was considered statistically significant.