What Kind of Gastric Tumor Is This?

Oscar M. Crespin, MD; Ali Kagan Coskun, MD; Brant K. Oelschlager, MD; Carlos A. Pellegrini, MD


January 15, 2014

Histologic Properties of Gastric Leiomyoma

To differentiate GLM from GIST, histologic properties are considered. On histologic examination, GISTs show higher cellularity causing basophilic staining properties, whereas GLMs are less cellular tumors creating an eosinophilic pattern.

The process of differential diagnosis is ultimately aided by immunohistochemical studies showing that GLMs are positive for desmin and smooth-muscle actin. GIST markers, such as CD34 and CD117 (c-kit), are usually negative for desmin.[8,9]

Surgical Approach to Gastric Leiomyoma

The first laparoscopic GLM resection was reported in 1992 and was performed for a GLM found incidentally during laparoscopic cholecystectomy.[9]

The procedure type is usually chosen according to location, size, extension, and the stage of the tumor at the preoperative period. However, sometimes the surgical strategy can be changed according to the findings at the moment of the operation.

Laparoscopic surgery for GLM offers the usual advantages of a minimally invasive approach.[10]


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