What Kind of Gastric Tumor Is This?

Oscar M. Crespin, MD; Ali Kagan Coskun, MD; Brant K. Oelschlager, MD; Carlos A. Pellegrini, MD

Disclosures

January 15, 2014

Diagnosis of Gastric Leiomyoma

The clinical diagnosis can be made by endoscopic ultrasonography showing the 5-layered structure of the gastrointestinal wall, thereby distinguishing it from hemangioma, cyst, and lipoma of the gastrointestinal wall.

By light microscopy alone, the distinction among GISTs and leiomyomas can be difficult because the histologic findings seen on hematoxylin and eosin-stained sections do not reliably or specifically relate to the immunophenotype or the molecular genetics of the lesions. The distinction between leiomyoma and GIST is usually based on immunohistochemical and molecular analytic techniques.[5,6,7]

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