The Differential Diagnosis of Systemic Sclerosis

Alan Tyndall; Susanna Fistarol

Disclosures

Curr Opin Rheumatol. 2013;25(6):692-699. 

In This Article

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Key Points

  • Suspected SSc without Raynaud's phenomenon, ANA or capillaroscopy changes should raise major doubts as to the diagnosis.

  • Puffy fingers, Raynaud's phenomenon, positive SScspecific autoantibodies and capillaroscopy changes indicate early SSc, even if skin thickening proximal to the metacarpophalangeal joints is not present.

  • An atypical case of SSc should always include skin biopsy (including fascia), paraprotein and focused system review to exclude mimics of SSc including paraneoplastic conditions.

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