It has been reported a removal-free survival of 81% at 7 years, 88.4% at 10 years and 94% at 20 years (Table 1). Although hemophilia patients who have had a TKR implant tend to be relatively young (mean age 35–45 years) in comparison with the group of patients with OA (mean aged 65–70 years), one publication states that prosthetic lifespan is greater in hemophilia patients than in patients with OA. If the available evidence, however, is analyzed as a whole, it is likely to conclude that the lifespan of prosthetic knee implants in hemophilic patients is shorter because of the increased risk of infection, due to the fact that many hemophiliac patients are HIV positive. However, larger comparative series would be required in order to confirm this assertion.
Expert Rev Hematol. 2013;6(6):637-642. © 2013 Expert Reviews Ltd.