Advances in Pneumococcal Antibiotic Resistance

Jae-Hoon Song


Expert Rev Resp Med. 2013;7(5):491-498. 

In This Article


During the past decades, epidemiology of pneumococcal resistance has been evolving with the widespread use of antibiotics, clonal spread of resistant strains and the introduction of PCV vaccination. Particularly, pneumococcal resistance is more serious in many Asian countries where antibiotics are widely abused, resistant clones are disseminated and PCV vaccination is not widely used. Given the clinical importance of pneumococcal diseases, accurate understanding of antimicrobial resistance and serotype distribution of S. pneumoniae is crucial. Continuous surveillance of pneumococcal epidemiology is strongly warranted together with antibiotic control programs and wide application of PCV13.