Effects of Habitual Coffee Consumption on Cardiometabolic Disease, Cardiovascular Health, and All-Cause Mortality

James H. O'Keefe, MD; Salman K. Bhatti, MD; Harshal R. Patil, MD; James J. DiNicolantonio, PHARMD; Sean C. Lucan, MD, MPH, MS; Carl J. Lavie, MD


J Am Coll Cardiol. 2013;62(12):1043-1051. 

In This Article

Coffee and CHF

A recent large meta-analysis reported a U-shaped relationship between coffee consumption and the incidence of CHF. Five independent prospective studies evaluating coffee consumption and CHF risk, from January 1966 through December 2011, were included in the meta-analysis. A total 6,522 heart failure events were recorded among the 140,220 participants during follow-up. A statistically significant association between coffee and CHF was observed, with the strongest inverse association noted for 4 servings per day with increased CHF risks for both higher and lower levels of coffee consumption (Fig. 3). There was no evidence that the relationship between coffee and risk of heart failure varied by sex or by baseline history of MI or diabetes.[29]

Figure 3.

Coffee and Risk of Heart Failure
Association between heart failure and cups of coffee per day compared with no consumption. Relative risk (solid line) and 95% CI (dashed lines). Adapted with permission from Freedman et al.25 and Mostofsky et al.29