Use of Daptomycin in the Treatment of Vancomycin-Resistant Enterococcal Urinary Tract Infections

A Short Case Series

Divya Pradeep Ramaswamy; Maria Amodio-Groton; Stephen J Scholand


BMC Urol. 2013;13(33) 

In This Article


In the current case series, daptomycin was shown to be a safe and effective therapeutic option in the management of VRE UTIs. Because of the increasing prevalence of VRE infection and the limited treatment options available, we anticipate that management of VRE UTIs will continue to be challenging for the clinician. Based on our experience, we believe that daptomycin is a valuable treatment option for problematic UTIs. These findings must be confirmed in larger randomized clinical trials. However, despite the lack of data about therapeutic options for VRE UTIs and the intrinsic limitations of descriptive case reports, our positive experience with daptomycin may be of value to the clinical community.