Periodontal Disease and Rheumatoid Arthritis

The Evidence Accumulates for Complex Pathobiologic Interactions

Clifton O. Bingham III; Malini Moni


Curr Opin Rheumatol. 2013;25(3):345-353. 

In This Article


The research reviewed highlights recent studies describing the relationships between rheumatoid arthritis and periodontal disease, and the potential biological mechanisms to explain these associations. The increased focus is resulting in a deeper appreciation of the oral manifestations of rheumatoid arthritis. As a consequence, dental assessment and attention to oral hygiene assume an increasingly important part of the clinical management of the rheumatoid arthritis patient. An increasing number of mechanistic studies are being reported that are likely to reveal additional interactions between these related diseases, and to provide insights for treatment and prevention. Closer attention to oral health in all patients will improve quality of life and address what is now recognized as an important rheumatoid arthritis comorbidity.