BRCA testing is expensive. The cost can range from several hundred to several thousand dollars, and it's not always covered by insurance. And the reality is that when you look at the general population, having a BRCA mutation is relatively uncommon. Only about 2% of the general population has a family history pattern that would suggest increased risk of having a BRCA mutation. BRCA genes are not the only ones linked to cancer. There are many more known cancer-related genes in addition to those not yet discovered. Although not all breast cancers are caused by BRCA mutations, these mutations do cause the majority of hereditary breast cancers, including 5%-10% of all breast cancers and 10%-15%of all ovarian cancers among white women in the United States. For Medicine Matters, I'm Dr. Sandra Fryhofer.
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Cite this: BRCA: Best Advice for Patients Who Worry - Medscape - May 28, 2013.