Paediatric Nonalcoholic Fatty Liver Disease

Anna Alisi; Guido Carpino; Valerio Nobili


Curr Opin Gastroenterol. 2013;29(3):279-284. 

In This Article


The literature of this last year contains several advances not only to further elucidate the genetic/pathogenetic mechanisms that lead to paediatric NAFLD but also allows to make many steps forward both on the diagnosis and therapy of children and adolescents with NAFLD.

However, detailed mechanisms of how cellular and organ cross-talk may functionally differentiate simple steatosis to NASH progression in children might suggest specific targeted therapeutic strategies that, if combined, may represent the winning approach against paediatric NAFLD.[49]