There are a number of published criteria to diagnose gout.[9,10] Several other conditions mimic the presentation of gout, including other crystal-induced arthritis, trauma, and septic joint. A typical presentation of gout includes severe pain, swelling, tenderness, fever, flulike symptoms, and often erythema of the joint that reaches peak intensity within 6 to 12 hours.[11,12] The attack is most common at the first metatarsophalangeal joint or great toe (also known as podagra), or at the knee. Several procedures and laboratory testing such as joint aspiration, radiography, serum uric acid concentrations, and kidney uric acid excretion may be considered if gout is suspected.
US Pharmacist. 2013;38(3):22-26. © 2013 Jobson Publishing