Temporomandibular Joint Arthroplasty With Human Amniotic Membrane

A Case Report

Florian Bauer, MD, DDS; Lukas M. Hingsammer, MD; Klaus-Dietrich Wolff, MD, DDS, PhD; Marco R. Kesting, MD, DDS, PhD


ePlasty. 2013;13 

In This Article

Abstract and Introduction


This case reports the usage of human amniotic membrane combined with a costochondral graft as an interpositional material in temporomandibular joint reconstruction for the first time in humans. Because of the favorable outcome 20 months postoperatively, it has to be considered as an approach bringing to light the antiadhesive potential of amniotic membrane. This case report must be regarded as initial spadework and should motivate other institutions to intensify their clinical research in this field. Because of the fact that currently used interpositional materials do not prevent the recurrence of temporomandibular joint ankylosis sufficiently, it is of great interest to establish a proper therapeutic intervention fulfilling these demands. Furthermore, the demonstrated antiadhesive properties of amniotic membrane highlight its multifaceted field of application. Nevertheless, further studies have to prove the findings reported in our case.


Gap arthroplasty and interpositional arthroplasty are the most commonly used therapeutic options to treat TMJ (temporomandibular joint) ankylosis. The major complication of both interventions is the recurrence of ankylosis. To date, no surgical or nonsurgical procedure can guarantee nonrecurrence; therefore, its effective therapy posts a clinical challenge. On the basis of the unsatisfactory results experienced with the current treatment options, our aim is to find an adequate new way to deal with TMJ ankylosis.[1–5]