Topol: 'Evidence Is Compelling' on Mediterranean Diet


March 07, 2013

In This Article

Clinical Impact of the Mediterranean Diet Study

We now have dietary evidence that is fairly compelling. The absolute size reduction was not large, but the fact that the Mediterranean diets tested in this trial had such a positive impact gives us some anchoring about a diet that does lower critical cardiovascular endpoints. For many years, there has been discussion about this low-fat diet and whether it had a meaningful clinical impact. At one point, the Mediterranean diet was very much supported by the American Heart Association and other organizations. Now we see that it appears to be superior. The trial has had criticism, particularly honing in on the low-fat control arm of the study, but nonetheless, the evidence is compelling.

Why is this trial unique? It was funded by the Spanish government. This is a country that isn't known these days for having extraordinary resources to fund research, but the government of Spain got behind an important trial, perhaps the most impressive diet-randomized trial that has been performed. We have to give a lot of credit to them, because this trial was done with that level of funding and with superb investigators throughout the country of Spain, and it makes a lasting contribution. We are always in search of more information about what we eat, and this is welcome. It is particularly nice to know that you can have 7 glasses of wine or more each week and it might have a favorable effect.

We will be trying to highlight similar studies that are interesting, taking us across the whole spectrum of diagnostics, medical devices, genomics, wireless medicine, and topics such as diet and nutrition, to broaden some of the special coverage that we have at Medscape. Thanks very much for your attention.