Our data demonstrate a high prevalence of vitamin D deficiency in otherwise healthy young adults in the Boston, Massachusetts area. The prevalence was particularly high among black subjects, who are known to be at higher risk, as well as among Asian subjects who are less well-described. Otherwise healthy white subjects also had significant rates of vitamin D deficiency. The predictions generated from this logistic regression model may serve as a guide to clinicians faced with the challenge of deciding whom to screen or empirically treat for vitamin D deficiency.
We wish to thank the staff of the Mallinckrodt General Clinical Research Center, Massachusetts General Hospital, Boston, Massachusetts, for their care of the subjects in these studies and Brian Healy, PhD, for statistical advice.
This work was supported by the following grants: National Institutes of Health grants K23DK073356 (to Dr. Sherri-Ann M. Burnett-Bowie), R01AG030545 (to Dr. Joel S. Finkelstein), K24DK02759 (to Dr. Joel S. Finkelstein), and M01RR01066 (to the Harvard Clinical and Translational Science Center, Boston, Massachusetts); an investigator-initiated grant from Solvay Pharmaceuticals, Inc., Brussels, Belgium (to Dr. Joel S. Finkelstein); a Massachusetts General Hospital Physician-Scientist Development Award, a Boston Area Diabetes and Endocrinology Research Center Grant, and a Claflin Distinguished Scholar Award (to Dr. Sherri-Ann M. Burnett-Bowie).
Endocr Pract. 2012;18(6):914-923. © 2012 American Association of Clinical Endocrinologists