Treatment of Nongastrointestinal Diseases: Autism
A role for microbiota in the pathogenesis of autism is supported by studies which show that the onset of autism is often accompanied by GI complaints and preceded by antibiotic use. Additionally, oral vancomycin has been shown to improve symptoms. In a single case series, the intestinal microbiota of 13 children with autism were analyzed and compared with nine children without the disease. The autistic children were found to have greater numbers and different types of clostridial species when compared with controls. There are published observations of improvement in autistic symptoms in two children after FMT and in five children who received daily cultured Bacteroidetes and Clostridia for several weeks (T. Borody, personal correspondence).
Curr Opin Gastroenterol. 2013;29(1):79-84. © 2013 Lippincott Williams & Wilkins