Review Article: Ulcerative Colitis, Smoking and Nicotine Therapy

P. C. Lunney; R. W. L. Leong


Aliment Pharmacol Ther. 2012;36(11):997-1008. 

In This Article

Materials and Methods

A literature search was conducted through Ovid MEDLINE (1946 to present) examining all published articles linked to the MeSH search terms 'ulcerative colitis' and 'smoking' or 'nicotine'. Relevant articles were identified through manual review. Furthermore, the reference lists of these articles were reviewed to include further appropriate articles. Randomised controlled studies were used that compared nicotine against placebo or conventional treatments. In addition, meta-analyses were reviewed due to small sample sizes of most studies.