Obesity Tied to Urinary Storage Problems

November 14, 2012

By David Douglas

NEW YORK (Reuters Health) Nov 14 - Obese men and women have twice the prevalence of nocturia compared to normal-weight adults, according to researchers.

"Our results suggest not only an additional rationale for weight reduction in people seeking medical attention for urinary storage symptoms but also highlight the diversity between such symptoms," Dr. Kari A. O. Tikkinen, who is currently at McMaster University, Hamilton, Ontario, told Reuters Health by email.

As reported October 24th online in The Journal of Urology, Dr. Tikkinen of the University of Helsinki, Finland and colleagues sent questionnaires to 6,000 randomly selected Finns and received responses from 3,727 (62.4%).

After adjustment, obesity was significantly associated with nocturia in both men (odds ratio, 2.0) and women (odds ratio, 2.4). This was not the case for urgency in either men or women.

In men, obesity was associated with urinary frequency (odds ratio 2.0). In women it was associated with both stress urinary incontinence (odds ratio, 1.9) and urgency urinary incontinence (odds ratio, 3.0). These incontinence symptoms were not common enough in men to allow accurate analysis.

The results overall, say the investigators "highlight the importance for assessment of specific symptoms and potential confounding factors."

Depending on the specificity of the question used to elicit symptom information, they add, "the interpretation of an association between body mass index and urgency and/or overactive bladder may be muddled." Several previous studies have used a composite symptom definition.

The team, however, points out that "the validity of self-report has not been established for all the characteristics considered, and the cross-sectional study design precludes conclusions about causality. These results from the Finnish population may not be generalizable to all other groups."

Nevertheless, Dr. Tikkinen concludes, the findings may help lead "to discovery of more effective treatment modalities in the future."

SOURCE: https://bit.ly/RUhdYA

J Urol 2012.