Intraocular Tuberculosis

Reema Bansal; Aman Sharma; Amod Gupta


Expert Rev Ophthalmol. 2012;7(4):341-349. 

In This Article


Diagnosis and treatment of TB remains a challenge especially in the developing world, which bears the majority of the global disease burden.[2] There are increasing reports of TB as a cause of uveitis from various regions of the world.[3–5] In the Sverdlovsk region of Russia, intraocular TB ranked fourth among extrapulmonary TB, following involvement of the urinary tract, peripheral lymph nodes, and bones and joints.[6] Ocular involvement in patients with systemic TB is uncommon and only 1.2–1.39% of patients with pulmonary TB may have intraocular TB.[7,8] However, in a series of 100 randomly selected patients with culture-proven systemic TB seen in a university hospital in Spain, 18 (18%) were found to have intraocular TB.[9] On the other hand, in a series of 494 patients with presumed intraocular TB, only 15 (3.03%) patients showed evidence of concurrent systemic TB disease.[10] Prevalence of TB as an etiology of uveitis has varied from 0.39% in South India,[11] 0.5% in the USA,[12] 4% in China,[13] 6.31% in Italy,[14] 6.9% in Japan,[4] 9.86% in North India[3] and 10.5% in Saudi Arabia.[15] Studies from the same institute in South India at different time periods have revealed changing patterns of uveitis.[16]