Latent and Subclinical Tuberculosis in HIV Infected Patients

A Cross-sectional Study

Meaghan M Kall; Katherine M Coyne; Nigel J Garrett; Aileen E Boyd; Anthony T Ashcroft; Iain Reeves; Jane Anderson; Graham H Bothamley


BMC Infect Dis. 2012;12(7) 

In This Article


Screening for TB in those with HIV infection and without symptoms in London (UK) yielded approximately 10% with latent infection and 1% with active disease. This yield of latent and active TB was greater than typically found in contact tracing, which should encourage health care workers to implement IGRA-based TB screening in the HIV clinic. There was a high completion rate for preventive treatment in those with a positive test result, and follow up of treated individuals will provide valuable insights into the long-term effects of preventive treatment.