Oral Mucosal Decontamination With Chlorhexidine for the Prevention of Ventilator-Associated Pneumonia in Children

A Randomized, Controlled Trial

Meghna Raju Sebastian, MD; Rakesh Lodha, MD; Arti Kapil, MD; Sushil K. Kabra, MD


Pediatr Crit Care Med. 2012;13(5):E305-310. 

In This Article


The oral mucosal application on 1% chlorhexidine gel did not prevent the development of VAP in children between 3 months and 15 yrs admitted to our PICU. It also did not have any effect on the duration of ventilation, stay in ICU or hospital, and mortality. Further evaluation of chlorhexidine, particularly in higher concentrations, is required in the pediatric population.