Meta-analysis: Probiotics in Antibiotic-Associated Diarrhoea

E. J. Videlock; F. Cremonini


Aliment Pharmacol Ther. 2012;35(12):1355-1369. 

In This Article


The aim of the present study was to provide an updated meta-analysis of randomised, controlled trials of probiotics in the prevention of AAD. The research questions were (i) Do probiotics reduce the incidence of AAD? (ii) Do probiotics reduce the incidence of AAD during treatment for H. pylori? (iii) Do the effects of probiotics in AAD vary between children and adults? and (iv) What probiotic species are more efficacious in preventing AAD? For the purpose of this meta-analysis, studies of the effect of probiotic in preventing occurrence and treating C. difficile-associated diarrhoea and colitis were not included.


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