In a general practice setting for patients complaining of moderate heartburn, Gaviscon® (4 × 10 mL/day) is an effective short-term treatment option in mild-to-moderate GERD, in terms of onset of a first 24-h heartburn-free period after initial dosing. It proved non-inferior to omeprazole 20 mg/day, and is thus a relevant and effective alternative treatment in case of moderate and episodic symptoms of GERD as managed in general practice.
DP, MAB and MC designed the study. FL participated in the design. MC conducted the data collection and designed and carried out the statistical analysis. DP wrote the article. All authors participated in critical revision of the manuscript and have seen and approved the final version. DP is the guarantor of this trial.
The study was funded by an unrestricted grant from Reckitt Benckiser Healthcare France.
Data collection and analyses were undertaken by Mediscan (MC) and received funding from Reckitt Benckiser Healthcare France. Writing support was provided by Fabienne Peretz, independent medical writer and funded by Reckitt Benckiser Healthcare France.
The authors had full and sole responsibility for the study design, data collection, statistical analysis, and interpretation of the data and for the writing of the report. The authors had complete independence as to the design, integrity and publication of the study, without any intervention from the pharmaceutical partner.
BMC Gastroenterol. 2012;12(18) © 2012 BioMed Central, Ltd.
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