Effects of Analgesic and Anesthetic Medications on Lower Urinary Tract Function

Sammy E. Elsamra, MD; Pamela Ellsworth, MD, FAAP, FACS


Urol Nurs. 2012;32(2):60-67. 

In This Article


Commonly used anesthetic and analgesic agents can have predictable effects on the LUT system. A condensed summary of the effect of anesthetics and analgesics on the LUT has been provided in Table 1. Opioids, NSAIDS, and anesthetics all tend to result in increased risk of urinary retention, with intrathecal delivery resulting in the highest rates of POUR. Ketamine, an anesthetic of abuse, is associated with severe and irreversible LUT damage.


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