Comparison of Recommendations: Metabolic and Renal Factors
Class II b
Measurement of HbA1C may be reasonable for cardiovascular risk assessment in asymptomatic adults without a diagnosis of diabetes (Khaw et al., 2004; Khaw & Wareham, 2006; Knowler et al., 2002; Lachin et al., 2007; Selvin et al., 2004; Selvin et al., 2010). (Level of Evidence: B)
Class II b
In asymptomatic adults at intermediate risk without hypertension or diabetes, urinalysis to detect microalbuminuria might be reasonable for cardiovascular risk assessment (Arnlov et al., 2005). (Level of Evidence: B)
CKD testing is not routinely recommended if the 10-year predicted risk is <5% without specific CKD or CVD risk factors, either for CKD detection or CVD risk assessment. (Classification of recommendation: III [against routine measurement]; Level of evidence: C)
CKD testing, including serum creatinine for GFR [glomerular filtration rate] estimation and microalbuminuria, for primary prevention should be performed for all individuals with hypertension, diabetes mellitus, family history of CKD, and those at intermediate risk (10% to 20%) for CVD. In addition, measurement of serum creatinine for GFR estimation should be performed in all individuals >65 years old. Individual decisions are recommended in those with other CKD risk factors. (Classification of recommendation: IIa; Level of evidence: B)
No recommendations provided.
AHRQ © 2012
Agency for Healthcare Research and Quality (AHRQ)
Cite this: Assessing Cardiovascular Risk: Guideline Synthesis - Medscape - Mar 01, 2012.