Assessing Omega-3 Fatty Acid Supplementation During Pregnancy and Lactation to Optimize Maternal Mental Health and Childhood Cognitive Development

Chelsea M Klemens; Kataneh Salari; Ellen L Mozurkewich


Clin Lipidology. 2012;7(1):93-109. 

In This Article

Other Factors that may Influence Fatty Acid Transfer to the Fetal Compartment

Fatty acid transfer across the placenta may also be influenced by a number of pregnancy complications, including gestational diabetes mellitus and intrauterine growth restriction.[71] For example, available studies demonstrate that placental long-chain PUFA uptake is increased but placental transport of long-chain PUFA to the fetal compartment is impaired in pregnancies complicated by gestational diabetes mellitus.[71] Similarly, in pregnancies complicated by intrauterine growth restriction, fetal cord blood ratios of the long-chain PUFAs DHA and ARA and the EFA precursors LA and ALA have been demonstrated to be significantly altered.[45,46,71]


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