New Developments in the Understanding and Management of Persistent Pain

Herta Flor PhD


Curr Opin Psychiatry. 2012;25(2):109-113. 

In This Article


Although recent scientific evidence has shown that chronic pain leads to changes in many brain regions, the responsiveness of pain to plastic changes also opens the door for new intervention methods, which rely on stimulation, behavioral training or pharmacological interventions that prevent maladaptive memory formation or enhance extinction. This article focused on the role of learning and memory mechanisms in the development and maintenance of chronic pain and outlined implications for new treatment approaches.


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