Ovarian Actions of Estrogen Receptor-β

An Update

Ann E. Drummond, Ph.D.; Peter J. Fuller, B.Med.Sci., M.B.B.S., Ph.D., F.R.A.C.P.

Disclosures

Semin Reprod Med. 2012;30(1):32-38. 

In This Article

Conclusion

ERβ plays an essential role in ovarian function; changes in expression or activation of ERβ may have clinical consequences that take the form of infertility or cancer. Future studies need to elucidate the structure of the physiologically active dimer, identify genes specifically regulated by ERβ in the ovary, and address the role of coactivators and corepressors in ERβ signaling.

Comments

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